Parathyroid hormone in renal transplanted recipients; a single center study
نویسندگان
چکیده
This investigation, aimed to study of intact parathormone (iPTH) and calcium (Ca) in a group of kidney transplanted patients and also we aimed to test the relationship of iPTH with various demographic data of kidney transplanted recipients. We studied 72 kidney transplanted persons with mean ages of 44±12 years. In this study, mean iPTH was 18.4±8.2 Pg/mL (median=16.5). A negative correlation of iPTH with creatinine clearance (r=-0.44, p<0.001) was seen. There was no any association between the time of kidney transplantation and serum iPTH (p>0.05). In contrast to previous findings, in our patients, there was not secondary hyperparathyroidism. The results revealed suppressed PTH secretion. The reason may be due to excessive intake of calcium and Vitamin D analogues, which may suppress parathyroid hormone secretion.
منابع مشابه
Paricalcitol for secondary hyperparathyroidism in renal transplantation.
Secondary hyperparathyroidism contributes to post-transplant CKD mineral and bone disorder. Paricalcitol, a selective vitamin D receptor activator, decreased serum parathyroid hormone levels and proteinuria in patients with secondary hyperparathyroidism. This single-center, prospective, randomized, crossover, open-label study compared the effect of 6-month treatment with paricalcitol (1 μg/d fo...
متن کاملارزیابی فعالیت آنتیاکسیدانی کلوتو در بیماران همودیالیز و پیوند کلیه
Received: 16 Aug , 2015 Accepted: 22 Oct , 2015 Abstract Background & Aims: The aim of this study was to evaluate serum levels of antioxidant property Klotho by examining 8-hydroxy-2'- deoxyguanosine (8-OHdG), as a marker of oxidative damage in nucleic acids in patients with hemodialysis and kidney transplantation. Materials & Methods: Serum samples from 45 patients undergoing hem...
متن کاملNonfunctioning allografts play an important role in parathyroid hormone and calcitonin metabolism.
Dr. Mehmet Şükrü Sever Ataköy, 4. Kisim, TO Blok No: 216, D:15 Bakirköy İstanbul (Turkey) Dear Sir, The kidneys (together with the liver) are responsible for most of the metabolism of polypeptide hormones; furthermore some hormones such as calcitonin (CT) and the N-terminal fragment of parathyroid hormone (PTH) are not metabolized by the liver, hence the role of the kidneys becomes more importa...
متن کاملPosttransplantation hyperparathyroidism: demonstration of retained control of parathyroid function by plasma ionized calcium.
Persistent hyperparathyroidism is a common complication of successful renal transplantation. This study sought to address several generally held assumptions concerning this endocrine disorder, i.e., it represents an autonomous condition that involutes with time. Eight normal subjects and 13 renal transplant patients with hyperparathyroidism were studied. Ten blood samples for simultaneous measu...
متن کاملMicrosoft Word - NEF460BF
Dr. Mehmet Şükrü Sever Ataköy, 4. Kisim, TO Blok No: 216, D:15 Bakirköy İstanbul (Turkey) Dear Sir, The kidneys (together with the liver) are responsible for most of the metabolism of polypeptide hormones; furthermore some hormones such as calcitonin (CT) and the N-terminal fragment of parathyroid hormone (PTH) are not metabolized by the liver, hence the role of the kidneys becomes more importa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2013